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KMID : 1156220180440040370
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Journal of Environmental Health Sciences
2018 Volume.44 No. 4 p.370 ~ p.379
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Relationship between Bisphenol A Exposure and Obesity in Korean Adults from the Second Stage of KoNEHS (2012-2014)
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Hwang Moon-Young
Lee Young-Mee
Jung Soon-Won
Hong Soo-Yeon
You Ji-Yong
Park Chung-Hee
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Abstract
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Objectives: Bisphenol A (BPA) has been extensively used in a variety of consumer products, resulting in widespread non-occupational human exposure. It is often detected in the human body. Studies have reported many health effects associated with endocrine and metabolic disruptions, including obesity, diabetes, hypertension, and cardiovascular diseases. This study was performed to explain the relationship between BPA exposure and obesity in the Korean adult population.
Methods: The second stage of the Korean National Environmental Health Survey (KoNHES) was conducted from 2012 to 2014 with 6,478 persons participating. Using the results of the survey, we analyzed the exposure levels for BPA and the influence on obesity of BPA.
Results: In model 1, the volume-based measure concentration of BPA, total, female and the 30s to 60s age group were positively related with BMI. In model 2, creatinine adjusted as a covariate and positive associations for BPA with BMI were observed in the female group and was marginally significantly associated in low body weight group. In model 3, creatinine adjusted (g/g-creatinine), BPA exposure, and BMI were positively related with sex, in females, and there was a marginally significant association with the low body weight group in the BMI categories. BMI was significantly associated with BPA in the female group in all three models.
Conclusion: This study added further evidence that exposure to EDCs, include bisphenol A, is related with obesity among the general population. Given the environmental health concerns over BPA, it is necessary to develop comprehensive measures to reduce BPA exposure.
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KEYWORD
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Biomonitoring, Bisphenol A, Obesity, BMI, KoNEHS
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